Research

Dr. Glover directs the Affective Neuroscience Laboratory at KSU, an interdisciplinary research and teaching program that primarily examines biological factors (e.g., sex and steroid hormones) and environmental factors (e.g., exposure to trauma, racism, or other adversities), associated with risk for psychiatric illness in a healthy population of primarily young adults. She is currently the PI on an NIH R15 grant project that uses translational models of conditioned fear and anxiety to characterize the mechanisms by which ovarian steroid hormones regulate fear- and anxiety-related behaviors in women. Dr. Glover’s background in translational neuroscience research began with using rodent models of fear learning and memory and using tools in psychophysiology and neuroimaging to characterize biomarkers of posttraumatic stress disorder (PTSD) in people with high risk for trauma exposure. 

Representitive Publications

Glover, E.M. (2020). Unlocking the potential of estradiol in PTSD symptom reduction: Is habituation the key? Biological Psychiatry: Biological psychiatry. Cognitive neuroscience and neuroimaging, 5(12), 1072–1074.

Glover, E.M., & Lauzon, O. (2018). Using a contrast illusion to teach principles of neural processing. Journal of Undergraduate Neuroscience Education, 17(1), A81-A88.

Michopoulos, V., Norrholm, S.D., Stevens, J.S., Glover, E.M., Rothbaum, B.O., Gillespie, C.F., Schwartz, A.C., Ressler, K.J., Jovanovic, T. (2017). Dexamethasone facilitates fear extinction and safety discrimination in PTSD: A placebo-controlled, double-blind study. Psychoneuroendocrinology, 83, 65-71.

Glover, E.M., Jovanovic, T., & Norrholm, S.D. (2015). Estrogen and Extinction of Fear Memories: Implications for Posttraumatic Stress Disorder Treatment. Biological Psychiatry, 78(3), 178-85.

Fani, N., King, T.Z., Brewster, R., Srivastava, A., Stevens, J.S., Glover, E.M., Norrholm, S.D., Bradley, B., Ressler, K.J., Jovanovic, T. (2015). Fear-potentiated startle during extinction is associated with white matter microstructure and functional connectivity. Cortex, 64, 249-259.

Norrholm, S.D., Glover, E.M., Stevens, J.S., Fani, N., Galatzer-Levy, I.R., Bradley, B., Ressler, K.J., Jovanovic, T. (2015). Fear load: The psychophysiological over-expression of fear as an intermediate phenotype associated with trauma reactions. Int J Psychophysiol, 98, 270-275.

Stevens, J.S., Almli, L.M., Fani, N., Gutman, D.A., Bradley, B., Norrholm, S.D., Reiser, E., Ely, T.D., Dhanani, R., Glover, E.M., Jovanovic, T., Ressler, K.J. (2014). PACAP receptor gene polymorphism  impacts fear responses in the amygdala and hippocampus. Proc Natl Acad Sci USA, 111(8), 3158-63.

Glover, E.M., Mercer, K.B., Norrholm, S.D., Davis, M., Duncan, E., Bradley, B., Ressler, K.J., & Jovanovic, T. (2013). Inhibition of fear is differentially associated with cycling estrogen levels in women. Journal of Psychiatry and Neuroscience, 38(5), 341-8.

Davis, T. A., Jovanovic, T., Norrholm, S. D., Glover, E. M., Swanson, M., Spann, S., & Bradley, B. (2013). Substance use attenuates physiological responses associated with PTSD among individuals with co-morbid PTSD and SUDs. Journal of Psychology and Psychotherapy, Suppl 7, S7-006-.

Stevens, J.S., Jovanovic, T., Fani, N., Ely, T.D., Glover, E.M., Bradley, B., Ressler, K.J. (2013) Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder. Journal of Psychiatric Research, 47(10), 1469-1478.

Fani, N., Gutman, D., Tone, E., Almli, L., Mercer, K.B., Davis, J., Glover, E., Jovanovic, T., Bradley, B., Dinov, I., Binder, E., Ressler, K.J. (2013). FKBP5 modulates attention bias for threat: associations with hippocampal function and morphology. JAMA Psychiatry,70(4), 392-400.

Glover, E.M., Jovanovic, T., Mercer, K.B., Kerley, K., Bradley, B., Ressler, K.J., & Norrholm, S.D. (2012) Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder. Biological Psychiatry, 72(1):19-24.

Jovanovic, T., Ely, T, Fani, N., Glover, E.M., Gutman, D., Tone, E., Norrholm, S.D., Bradley, B., Ressler, K.J. (2012). Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample. Cortex, 49(7), 1884-91.

Fani, N., King, T., Jovanovic, T., Glover, E.M., Bradley, B., Ely, T., Gutman, D., Ressler, K.J. (2012). White matter integrity in highly-traumatized adults with and without post-traumatic stress disorder. Neuropsychopharmacology, 37(12), 2740-6.

Glover, E.M., Phifer, J.E., Crain, D. F., Norrholm, S.D., Davis, M., Bradley, B., Ressler, K.J., & Jovanovic, T. (2011). Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures. Depression & Anxiety, 21(12),1058-66.

Glover, E.M., Ressler, K.J., & Davis, M. (2010). Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories. Learning & Memory, 17(11),577-581.

Glover, E.M., Davis, M. (2008) Anxiolytic-like effects of morphine and buprenorphine in the rat model of fear-potentiated startle: tolerance, cross-tolerance, and blockade by naloxone. Psychopharmacology (Berl). 198(2),167-80.